Biology & Epidemiology of COVID-19 and SARS-CoV2

A) COVID-19 biology: An introductory course for non-biologists, explaining the key proteins of this virus and its presence in the context of other related viruses. Its action on human beings, covering effects on various organs. This will be followed by an introduction to specific effects, such as IgA, Opsin, IgG, IgM, cytokine storm, cytotoxic response, vasodilation, blood coagulation and clotting, cardiac arrhythmia, fibrosis and glassy lungs, inflammation and type 2 diabetes, oxidative stress, ROS-NOS signaling, oxygen levels and heme in as less technical jargon as possible. Followed by this there will be classes on common methods of dealing with and preventing infection from SARS-CoV2.

B) Basics of Virology: This course is for biologists to get to know virology better. Covid19 times have placed the role of viruses in public eye and informing non-biologists what are viruses is the need of the hour. Origin of viruses: plasmids, bacteria and other ideas, Kinds of viruses. How viruses cause disease? Common plant viruses. Common animal viruses. Common bacterial and archaeal viruses. Virus envelope. Virus genomes. Viral replication. Common human disease causing viruses? Latent infections. Cytopathic effects. Epidemics and pandemics. Host defense mechanisms. Vaccines. Antiviral drugs. Positive roles in biotechnology. Case study of SARS-CoV2.

C) How to develop a vaccine: Vaccine safety and effectiveness. Adjuvants. Vaccination schedule. Adverse effects. Inactivated vaccine. Toxoid, subunit, and conjugate vaccine. Heterotypic vaccines and cross immunity. Dendretic cell vaccine. DNA vaccine. RNA vaccine. T-cell receptor vaccine. Preservatives and excipients in vaccines. Vaccination schedule. Economics of vaccination; development, production. Delivery system. Plants as bioreactors for vaccine production. Vaccination for veterinary uses.

D) Diabetes and COVID-19 – Dangerous liasons: Types of diabetes (i, ii) , Disease mechanism of COVID-19 (how could the virus target pancreatic cells) , Diabetes increases the risk of COVID-19 – how and why? , Post-COVID-19 -> diabetes (morphological changes in cells, mechanism of the same, dedifferentiation, ) , Managing diabetes through healthy food choices and exercise, Enhancing immunity through food and spices , Herbal solutions for convalescing individuals.